The Ducati Desmosedici RR is a limited production road-legal version of the Desmosedici MotoGP racebike. Ducati made 1,500 Desmosedici models for public purchase. The bike was launched at the 2006 Italian MotoGP event.

In 2004, Ducati announced that a low volume bespoke replica of the Desmosedici would be available beginning in 2006. Termed the Desmosedici RR (Racing Replica), it was claimed to be the first true road replica of a MotoGP racing bike. Priority for ordering was given to Ducati 999R owners, with production projected at one bike per day at a retail cost of US$72,500 and £40,000. The price included a three year warranty and servicing, cover, and a racing kit including a race-only exhaust system, a slip-on muffler, and complementary fuel and ignition mapping in a “race ECU”. It also included enough sponsor stickers to fill both sides of the bike.

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